The Role of Toxicological Interactions in Lung Injury

Interactions between two or more toxic agents can produce lung damage by chemical-chemical interactions, chemical-receptor interactions or by modification, by a first agent, of the cell and tissue response to a second agent. Interactions may occur by simultaneous exposure and if exposure to the two...

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Bibliographische Detailangaben
Veröffentlicht in:	Environ. Health Perspect.; (United States) 1984-04, Vol.55, p.139-148
Hauptverfasser:	Witschi, H. P., Hakkinen, P. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	560306 - Chemicals Metabolism & Toxicology- Man- (-1987) AEROSOLS Air Pollutants - toxicity AIR POLLUTION Animals ANTIOXIDANTS Binding, Competitive BODY Chemical hazards COLLOIDS DISEASES DISPERSIONS DOCUMENT TYPES Dosage Drug Interactions ELEMENTS Enzyme Induction - drug effects Free Radicals Humans INJURIES Lung Diseases - chemically induced Lung injury LUNGS MATERIALS Metabolism Mixed Function Oxygenases - metabolism MIXTURES Monograph on Pulmonary Toxicology NONMETALS ORGANS OXYGEN Oxygen - toxicity POLLUTION RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RESPIRATORY SYSTEM RESPIRATORY SYSTEM DISEASES REVIEWS SOLS Subcellular Fractions - metabolism Superoxides SYNERGISM Time Factors TOXIC MATERIALS TOXICITY Toxicology
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