Salmeterol inhibition of mediator release from human lung mast cells by β‐adrenoceptor‐dependent and independent mechanisms

1 The long‐acting β2‐adrenoceptor agonist, salmeterol (10−9–10−5 M), inhibited the IgE‐mediated release of histamine from human lung mast cells (HLMC) in a dose‐dependent fashion. Additional β‐adrenoceptor agonists were studied and the rank order of potency for the inhibition of histamine release fr...

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