Histamine‐induced biphasic macromolecular leakage in the microcirculation of the conscious hamster: evidence for a delayed nitric oxide‐dependent leakage

1 Late effects (up to 3 h) of intravenously‐injected histamine on FITC‐dextran extravasation were investigated in the conscious hamster, by use of computer‐assisted image analysis of fluorescence distribution in a microscopic window of dorsal skin fold preparations. This analysis allowed measurement...

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Veröffentlicht in:	British journal of pharmacology 1998-03, Vol.123 (5), p.943-951
Hauptverfasser:	Gimeno, G, Carpentier, P H., Desquand‐Billiald, S, Hanf, R, Finet, M
Format:	Artikel
Sprache:	eng
Schlagworte:	aminoguanidine Animals Biological and medical sciences Capillary Permeability - drug effects Capillary Permeability - physiology Cell receptors Cell structures and functions Cricetinae Dexamethasone - pharmacology Dose-Response Relationship, Drug Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Guanidines - pharmacology Histamine - pharmacology L‐arginine Male Mesocricetus Microcirculation - drug effects Molecular and cellular biology Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine) NG-Nitroarginine Methyl Ester - pharmacology NG‐nitro‐L‐arginine methyl ester Nitric Oxide - physiology Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase Type II omega-N-Methylarginine - pharmacology permeability Polysaccharides - pharmacology
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