Fidelity in functional coupling of the rat P2Y1 receptor to phospholipase C

1 The rat homologue of the P2Y1 receptor has been heterologously expressed in 1321N1 human astrocytoma cells and in C6 rat glioma cells. 2 As has been shown previously for the turkey and human P2Y1 receptors, the rat P2Y1 receptor expressed in either cell type responded to 2MeSATP with increases in...

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Veröffentlicht in:	British journal of pharmacology 1997-11, Vol.122 (6), p.1021-1024
Hauptverfasser:	Schachter, Joel B., Boyer, José L., Li, Qing, Nicholas, Robert A., Harden, T. Kendall
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Adenosinic and purinergic receptors Adenylyl Cyclases - metabolism Animals Biological and medical sciences Cell receptors Cell structures and functions Colforsin - pharmacology cyclic AMP Cyclic AMP - metabolism Enzyme Activation Fundamental and applied biological sciences. Psychology Humans inositol lipid signalling Molecular and cellular biology P2Y1 receptor purine nucleotide Pyridoxal Phosphate - analogs & derivatives Pyridoxal Phosphate - pharmacology Rats Receptors, Purinergic P2 - metabolism Receptors, Purinergic P2Y1 signalling Thionucleotides - pharmacology Tumor Cells, Cultured Turkeys Type C Phospholipases - metabolism
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