Examination of the role of endopeptidase 3.4.24.15 in Aβ secretion by human transfected cells

We have taken advantage of our recent development of highly potent and specific phosphinic inhibitors of endopeptidase 3.4.24.15 to examine the putative contribution of the enzyme in the secretion of Aβ by HK293 transfected cells overexpressing the wild type and the Swedish (Sw) double mutated form...

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