The effect of cystectomy on antitissue antibodies in interstitial cystitis
Cystectomy was carried out on three patients with interstitial cystitis who had elevated antibody titres against cell nuclei and crude kidney homogenate. These titres decreased within 12 months of the operation below pathological levels. This suggests that the stimulus to antibody production lies in...
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Veröffentlicht in: | Clinical and experimental immunology 1973-11, Vol.15 (3), p.457-460 |
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creator | Jokinen, E J Oravisto, K J Alfthan, O S |
description | Cystectomy was carried out on three patients with interstitial cystitis who had elevated antibody titres against cell nuclei and crude kidney homogenate. These titres decreased within 12 months of the operation below pathological levels. This suggests that the stimulus to antibody production lies in the diseased tissue of the bladder. |
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These titres decreased within 12 months of the operation below pathological levels. 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These titres decreased within 12 months of the operation below pathological levels. This suggests that the stimulus to antibody production lies in the diseased tissue of the bladder.</description><subject>Antibodies, Antinuclear</subject><subject>Autoantibodies - analysis</subject><subject>Cell Nucleus</subject><subject>Cystitis - immunology</subject><subject>Humans</subject><subject>Kidney - immunology</subject><subject>Muscle, Smooth - immunology</subject><subject>Short Communications</subject><subject>Stomach - immunology</subject><subject>Thyroid Gland - immunology</subject><subject>Urinary Bladder - surgery</subject><issn>0009-9104</issn><issn>1365-2249</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUE1LAzEUDKLUWv0Jwp68LeR7NxdBip8UvNRzyCYvNrK7qZus0H_vthZRePBmmHkz8E7QnDApSkq5OkVzjLEqFcH8HF2k9DFRKSWdoRkXnAlRzdHLegMFeA82F9EXdpfyBGO3K2JfmD6HHFIa4QCb6AKkIvTTZBjSXjTt4WZvu0Rn3rQJro57gd4e7tfLp3L1-vi8vFuVWypJLi2uuW-ayoDnytOGk4Y66hSVkrvKSQE1IRIbp7CwypOKUMykgkq5yljJ2ALd_uRux6YDZ6HPg2n1dgidGXY6mqD_K33Y6Pf4pYkQTOFqCrg5Bgzxc4SUdReShbY1PcQx6ZoSIhQhk_H6b9NvxfF77BuSKW6h</recordid><startdate>19731101</startdate><enddate>19731101</enddate><creator>Jokinen, E J</creator><creator>Oravisto, K J</creator><creator>Alfthan, O S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19731101</creationdate><title>The effect of cystectomy on antitissue antibodies in interstitial cystitis</title><author>Jokinen, E J ; Oravisto, K J ; Alfthan, O S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p261t-c084fbb7aef49f2b41b2d2d92664d7d65e81160ad905c9f17120369e79d7ac633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Antibodies, Antinuclear</topic><topic>Autoantibodies - analysis</topic><topic>Cell Nucleus</topic><topic>Cystitis - immunology</topic><topic>Humans</topic><topic>Kidney - immunology</topic><topic>Muscle, Smooth - immunology</topic><topic>Short Communications</topic><topic>Stomach - immunology</topic><topic>Thyroid Gland - immunology</topic><topic>Urinary Bladder - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jokinen, E J</creatorcontrib><creatorcontrib>Oravisto, K J</creatorcontrib><creatorcontrib>Alfthan, O S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical and experimental immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jokinen, E J</au><au>Oravisto, K J</au><au>Alfthan, O S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of cystectomy on antitissue antibodies in interstitial cystitis</atitle><jtitle>Clinical and experimental immunology</jtitle><addtitle>Clin Exp Immunol</addtitle><date>1973-11-01</date><risdate>1973</risdate><volume>15</volume><issue>3</issue><spage>457</spage><epage>460</epage><pages>457-460</pages><issn>0009-9104</issn><eissn>1365-2249</eissn><abstract>Cystectomy was carried out on three patients with interstitial cystitis who had elevated antibody titres against cell nuclei and crude kidney homogenate. These titres decreased within 12 months of the operation below pathological levels. This suggests that the stimulus to antibody production lies in the diseased tissue of the bladder.</abstract><cop>England</cop><pmid>4543557</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
subjects | Antibodies, Antinuclear Autoantibodies - analysis Cell Nucleus Cystitis - immunology Humans Kidney - immunology Muscle, Smooth - immunology Short Communications Stomach - immunology Thyroid Gland - immunology Urinary Bladder - surgery |
title | The effect of cystectomy on antitissue antibodies in interstitial cystitis |
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