Successful treatment of an infant with severe combined immunodeficiency by transplantation of bone marrow cells from an uncle

A 4½-month-old boy suffering from congenital severe combined immunodeficiency was successfully treated by transplantation of bone marrow-derived cells. His parents were cousins in the first degree. The donor was a 32-year-old maternal uncle, who was HL-A genotypically identical with the patient as w...

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Veröffentlicht in:	Clinical and experimental immunology 1973-01, Vol.13 (1), p.9-20
Hauptverfasser:	Vossen, J M, de Koning, J, van Bekkum, D W, Dicke, K A, Eysvoogel, V P, Hijmans, W, van Loghem, E, Rádl, J, van Rood, J J, van der Waay, D, Dooren, L J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Bone Marrow Cells Bone Marrow Transplantation Centrifugation, Density Gradient Feces - microbiology Genotype Histocompatibility Antigens Histocompatibility Testing Humans Immunoglobulin G - analysis Immunologic Deficiency Syndromes - genetics Immunologic Deficiency Syndromes - nursing Immunologic Deficiency Syndromes - therapy Infant Isoantigens - analysis Lymphocyte Activation Male Patient Isolators Pedigree Pharynx - microbiology Skin - microbiology Tissue Donors Transplantation, Homologous
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