Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity

The neural bHLH genes Mash1 and Ngn2 are expressed in complementary populations of neural progenitors in the central and peripheral nervous systems. Here, we have systematically compared the activities of the two genes during neural development by generating replacement mutations in mice in which th...

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Veröffentlicht in:Genes & development 2002-02, Vol.16 (3), p.324-338
Hauptverfasser: Parras, Carlos M, Schuurmans, Carol, Scardigli, Raffaella, Kim, Jaesang, Anderson, David J, Guillemot, François
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Sprache:eng
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