Tumour necrosis factor production in Falciparum malaria and its association with schizont rupture

To investigate the involvement of tumour necrosis factor (TNF) in human malaria, we studied TNF production in patients infected with Plasmodium falciparum, and in co-cultures of human mononuclear cells and malaria parasites in vitro. In the examined sample, plasma TNF levels of over 39 pg/ml were de...

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Veröffentlicht in:	Clinical and experimental immunology 1989-09, Vol.77 (3), p.361-366
Hauptverfasser:	KWIATKOWSKI, D, CANNON, J. G, MANOGUE, K. R, CERAMI, A, DINARELLO, C. A, GREENWOOD, B. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Child, Preschool Human protozoal diseases Humans Infectious diseases Leukocytes, Mononuclear - immunology Malaria Malaria - immunology Malaria - parasitology Medical sciences Parasitic diseases Plasmodium falciparum Protozoal diseases Tropical medicine Tumor Necrosis Factor-alpha - biosynthesis
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