Tetanus toxoid complexed with heterologous antibody can induce germinal centre formation and B cell memory in mice without evoking a detectable anti-toxin response

Fluid free tetanus toxoid (FTT) alone or FTT complexed in vitro at equivalence (EQ) or in antibody excess (ABEX) with anti-toxin contained in a human gammaglobulin preparation (HGG), or HGG alone, were injected into the hind leg footpads of mice. Anti-toxin titres of mouse serum were measured and co...

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Veröffentlicht in:	Clinical and experimental immunology 1989-04, Vol.76 (1), p.138-143
Hauptverfasser:	KRAFT, R, BUERKI, H, SCHWEIZER, T, HESS, M. W, COTTIER, H, STONER, R. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals B-Lymphocytes - immunology Biological and medical sciences Female Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Immunologic Memory Lymph Nodes - immunology Mice Mice, Inbred Strains Organs and cells involved in the immune response Tetanus Antitoxin - immunology Tetanus Toxoid - immunology
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