Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma

Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma

This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International seminars in surgical oncology 2006-07, Vol.3 (1), p.18-18, Article 18
Hauptverfasser: Quadros, Claudio Almeida, Vasconcelos, Alessandro, Andrade, Roque, Ramos, Rogério Santos, Studart, Eduardo, Nascimento, Geraldo, Trajano, André
Format: Artikel
Sprache:eng
Schlagworte:
Case Report
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 18
container_issue 1
container_start_page 18
container_title International seminars in surgical oncology
container_volume 3
creator Quadros, Claudio Almeida
Vasconcelos, Alessandro
Andrade, Roque
Ramos, Rogério Santos
Studart, Eduardo
Nascimento, Geraldo
Trajano, André
description This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carcinoma. The sarcoma presented as a fast growing tumour, 9.5 cm in the largest diameter, with skin, left breast, chest wall muscle and rib invasion. Neoadjuvant chemotherapy was performed with epirubicin and ifosfamide. Extended radical surgery according to oncological standards and soft tissue reconstruction were carried out. Despite bad prognostic features of high grade and large invasive sarcoma, the patient is currently, after 44 months of follow up, without local recurrence, or metastases, exceeding the 12.8-month mean recurrence period and mortality rate for these tumours larger than 8.1 cm (+/- 1.2 cm) as described in the literature.
doi_str_mv 10.1186/1477-7800-3-18
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1538603</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68735160</sourcerecordid><originalsourceid>FETCH-LOGICAL-b3618-efaf51430f6861c426a0789206647dd4c44fe4d70840fa7b03a549f60a2426f03</originalsourceid><addsrcrecordid>eNp1kU1v3CAQhlHVqPlorz1WnHpzCobF7KVSFDVJpUi9NGc0hsEmss0WcNSc-8dja1dpoqonhneGZ2Z4CfnI2TnnWn3hsmmqRjNWiYrrN-TkWXj7Ij4mpznfM1Zvl9s7csyVrmUt6hPy5zpGR-NcbByRgi-Y6IQR3P38AFOhtscxlh4T7B4pTI7i74KTQ0fznLpgYaAJM9oS4kR9TBToAKlDmsAFWNUqTG62y4M-dH3VLTrSNiHkQjOkpS28J0cehowfDucZubv69vPyprr9cf398uK2aoXiukIPfsOlYF5pxa2sFbBGb2umlGyck1ZKj9I1TEvmoWmZgI3cesVg2VV5Js7I1z13N7cjOotTSTCYXQojpEcTIZjXmSn0posPhm-EVkwsgIs9oA3xP4DXmWU7s5pgVhOMMFwvjM-HIVL8NWMuZgzZ4jDA8u1zNko3YsPVOu35vtCmmHNC_9yHM7N6_y_508v1_pYfzBZP0ECtog</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68735160</pqid></control><display><type>article</type><title>Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>Springer Nature OA Free Journals</source><source>BioMedCentral</source><source>PubMed Central</source><creator>Quadros, Claudio Almeida ; Vasconcelos, Alessandro ; Andrade, Roque ; Ramos, Rogério Santos ; Studart, Eduardo ; Nascimento, Geraldo ; Trajano, André</creator><creatorcontrib>Quadros, Claudio Almeida ; Vasconcelos, Alessandro ; Andrade, Roque ; Ramos, Rogério Santos ; Studart, Eduardo ; Nascimento, Geraldo ; Trajano, André</creatorcontrib><description>This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carcinoma. The sarcoma presented as a fast growing tumour, 9.5 cm in the largest diameter, with skin, left breast, chest wall muscle and rib invasion. Neoadjuvant chemotherapy was performed with epirubicin and ifosfamide. Extended radical surgery according to oncological standards and soft tissue reconstruction were carried out. Despite bad prognostic features of high grade and large invasive sarcoma, the patient is currently, after 44 months of follow up, without local recurrence, or metastases, exceeding the 12.8-month mean recurrence period and mortality rate for these tumours larger than 8.1 cm (+/- 1.2 cm) as described in the literature.</description><identifier>ISSN: 1477-7800</identifier><identifier>EISSN: 1477-7800</identifier><identifier>DOI: 10.1186/1477-7800-3-18</identifier><identifier>PMID: 16824232</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Case Report</subject><ispartof>International seminars in surgical oncology, 2006-07, Vol.3 (1), p.18-18, Article 18</ispartof><rights>Copyright © 2006 Quadros et al; licensee BioMed Central Ltd. 2006 Quadros et al; licensee BioMed Central Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b3618-efaf51430f6861c426a0789206647dd4c44fe4d70840fa7b03a549f60a2426f03</citedby><cites>FETCH-LOGICAL-b3618-efaf51430f6861c426a0789206647dd4c44fe4d70840fa7b03a549f60a2426f03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538603/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538603/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,24781,27903,27904,53769,53771,75484,75485</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16824232$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Quadros, Claudio Almeida</creatorcontrib><creatorcontrib>Vasconcelos, Alessandro</creatorcontrib><creatorcontrib>Andrade, Roque</creatorcontrib><creatorcontrib>Ramos, Rogério Santos</creatorcontrib><creatorcontrib>Studart, Eduardo</creatorcontrib><creatorcontrib>Nascimento, Geraldo</creatorcontrib><creatorcontrib>Trajano, André</creatorcontrib><title>Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma</title><title>International seminars in surgical oncology</title><addtitle>Int Semin Surg Oncol</addtitle><description>This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carcinoma. The sarcoma presented as a fast growing tumour, 9.5 cm in the largest diameter, with skin, left breast, chest wall muscle and rib invasion. Neoadjuvant chemotherapy was performed with epirubicin and ifosfamide. Extended radical surgery according to oncological standards and soft tissue reconstruction were carried out. Despite bad prognostic features of high grade and large invasive sarcoma, the patient is currently, after 44 months of follow up, without local recurrence, or metastases, exceeding the 12.8-month mean recurrence period and mortality rate for these tumours larger than 8.1 cm (+/- 1.2 cm) as described in the literature.</description><subject>Case Report</subject><issn>1477-7800</issn><issn>1477-7800</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNp1kU1v3CAQhlHVqPlorz1WnHpzCobF7KVSFDVJpUi9NGc0hsEmss0WcNSc-8dja1dpoqonhneGZ2Z4CfnI2TnnWn3hsmmqRjNWiYrrN-TkWXj7Ij4mpznfM1Zvl9s7csyVrmUt6hPy5zpGR-NcbByRgi-Y6IQR3P38AFOhtscxlh4T7B4pTI7i74KTQ0fznLpgYaAJM9oS4kR9TBToAKlDmsAFWNUqTG62y4M-dH3VLTrSNiHkQjOkpS28J0cehowfDucZubv69vPyprr9cf398uK2aoXiukIPfsOlYF5pxa2sFbBGb2umlGyck1ZKj9I1TEvmoWmZgI3cesVg2VV5Js7I1z13N7cjOotTSTCYXQojpEcTIZjXmSn0posPhm-EVkwsgIs9oA3xP4DXmWU7s5pgVhOMMFwvjM-HIVL8NWMuZgzZ4jDA8u1zNko3YsPVOu35vtCmmHNC_9yHM7N6_y_508v1_pYfzBZP0ECtog</recordid><startdate>20060707</startdate><enddate>20060707</enddate><creator>Quadros, Claudio Almeida</creator><creator>Vasconcelos, Alessandro</creator><creator>Andrade, Roque</creator><creator>Ramos, Rogério Santos</creator><creator>Studart, Eduardo</creator><creator>Nascimento, Geraldo</creator><creator>Trajano, André</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20060707</creationdate><title>Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma</title><author>Quadros, Claudio Almeida ; Vasconcelos, Alessandro ; Andrade, Roque ; Ramos, Rogério Santos ; Studart, Eduardo ; Nascimento, Geraldo ; Trajano, André</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b3618-efaf51430f6861c426a0789206647dd4c44fe4d70840fa7b03a549f60a2426f03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Case Report</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Quadros, Claudio Almeida</creatorcontrib><creatorcontrib>Vasconcelos, Alessandro</creatorcontrib><creatorcontrib>Andrade, Roque</creatorcontrib><creatorcontrib>Ramos, Rogério Santos</creatorcontrib><creatorcontrib>Studart, Eduardo</creatorcontrib><creatorcontrib>Nascimento, Geraldo</creatorcontrib><creatorcontrib>Trajano, André</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International seminars in surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Quadros, Claudio Almeida</au><au>Vasconcelos, Alessandro</au><au>Andrade, Roque</au><au>Ramos, Rogério Santos</au><au>Studart, Eduardo</au><au>Nascimento, Geraldo</au><au>Trajano, André</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma</atitle><jtitle>International seminars in surgical oncology</jtitle><addtitle>Int Semin Surg Oncol</addtitle><date>2006-07-07</date><risdate>2006</risdate><volume>3</volume><issue>1</issue><spage>18</spage><epage>18</epage><pages>18-18</pages><artnum>18</artnum><issn>1477-7800</issn><eissn>1477-7800</eissn><abstract>This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carcinoma. The sarcoma presented as a fast growing tumour, 9.5 cm in the largest diameter, with skin, left breast, chest wall muscle and rib invasion. Neoadjuvant chemotherapy was performed with epirubicin and ifosfamide. Extended radical surgery according to oncological standards and soft tissue reconstruction were carried out. Despite bad prognostic features of high grade and large invasive sarcoma, the patient is currently, after 44 months of follow up, without local recurrence, or metastases, exceeding the 12.8-month mean recurrence period and mortality rate for these tumours larger than 8.1 cm (+/- 1.2 cm) as described in the literature.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>16824232</pmid><doi>10.1186/1477-7800-3-18</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1477-7800
ispartof International seminars in surgical oncology, 2006-07, Vol.3 (1), p.18-18, Article 18
issn 1477-7800
1477-7800
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1538603
source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; Springer Nature OA Free Journals; BioMedCentral; PubMed Central
subjects Case Report
title Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T16%3A10%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Good%20outcome%20after%20neoadjuvant%20chemotherapy%20and%20extended%20surgical%20resection%20for%20a%20large%20radiation-induced%20high-grade%20breast%20sarcoma&rft.jtitle=International%20seminars%20in%20surgical%20oncology&rft.au=Quadros,%20Claudio%20Almeida&rft.date=2006-07-07&rft.volume=3&rft.issue=1&rft.spage=18&rft.epage=18&rft.pages=18-18&rft.artnum=18&rft.issn=1477-7800&rft.eissn=1477-7800&rft_id=info:doi/10.1186/1477-7800-3-18&rft_dat=%3Cproquest_pubme%3E68735160%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68735160&rft_id=info:pmid/16824232&rfr_iscdi=true