Lack of prostaglandin E2-mediated monocyte suppressive activity in newborn and mothers

An excess of adult blood adherent cells (monocytes) inhibits mitogen, antigen and allogeneic cell-induced lymphocyte proliferations. This inhibition is dependent on the number of the adherent monocytes in the cultures and is substantially reduced (by 60%) by indomethacin or anti-PGE2 antiserum. Newb...

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Veröffentlicht in:	Clinical and experimental immunology 1982-08, Vol.49 (2), p.377-385
Hauptverfasser:	Fischer, A, Durandy, A, Mamas, S, McCall, E, Dray, F, Griscelli, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cell Adhesion Dinoprostone Female Fetal Blood - immunology Fetal Blood - metabolism Humans Immunosuppression Indomethacin - pharmacology Infant, Newborn Lymphocyte Activation - drug effects Lymphocyte Culture Test, Mixed Monocytes - immunology Monocytes - metabolism Prostaglandins E - biosynthesis Prostaglandins E - physiology T-Lymphocytes - immunology
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