The effects of Plasmodium falciparum malaria on immune control of B lymphocytes in Gambian children

SUMMARY Children living in hyperendemic malarious regions have high immunoglobulin levels and an increased frequency of Burkitt's lymphoma. In a study of Gambian children which endeavours to explain these findings we showed that acute P. falciparum malaria caused spontaneous activation and grow...

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Veröffentlicht in:	Clinical and experimental immunology 1990-05, Vol.80 (2), p.213-218
Hauptverfasser:	WHITTLE, H. C., BROWN, J., MARSH, K., BLACKMAN, M., JOBE, O., SHENTON, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals B-Lymphocytes - immunology Biological and medical sciences Blymphocytes CD4-Positive T-Lymphocytes - physiology Cell Transformation, Viral - immunology Cells, Cultured Child Child, Preschool Epstein‐Barr virus immunoglobulins Herpesvirus 4, Human - immunology Human protozoal diseases Humans Immunoglobulin G - biosynthesis Immunoglobulin M - biosynthesis Infectious diseases Lymphocyte Activation - immunology Malaria Malaria - immunology Medical sciences Parasitic diseases Plasmodium falciparum Plasmodium falciparum malaria Protozoal diseases T-Lymphocytes, Cytotoxic - physiology Tropical medicine
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