Evaluation of a model for post‐partum arthritis and the role of oestrogen in prevention of MRL‐lpr associated rheumatic conditions

SUMMARY Sixty‐eight percent of female MRL‐lpr‐ mice developed a post‐partum exacerbation of their mild spontaneous arthritis within 30 days of parturition‐ The flare became evident between 5 and 15 days after delivery. Histologically it was characterized by a significant increase of subsynovial infl...

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Veröffentlicht in:	Clinical and experimental immunology 1994-10, Vol.98 (1), p.52-59
Hauptverfasser:	RATKAY, L. G., ZHANG, D., TONZETICH, J., LEVY, J. G., WATERFIELD, J. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals arthritis Arthritis, Experimental - physiopathology Arthritis, Rheumatoid - pathology Arthritis, Rheumatoid - physiopathology Arthritis, Rheumatoid - prevention & control Biological and medical sciences Disease Models, Animal Estradiol - physiology Estradiol - therapeutic use Experimental and animal immunopathology. Animal models Female Immunopathology Lupus Erythematosus, Systemic - physiopathology Medical sciences Mice Mice, Mutant Strains oestrogen post‐partum flare Puerperal Disorders - pathology Puerperal Disorders - physiopathology Puerperal Disorders - prevention & control systemic lupus erythematosus
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