Approaches to developing alternative and predictive toxicology based on PBPK/PD and QSAR modeling

Systematic toxicity testing, using conventional toxicology methodologies, of single chemicals and chemical mixtures is highly impractical because of the immense numbers of chemicals and chemical mixtures involved and the limited scientific resources. Therefore, the development of unconventional, eff...

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Veröffentlicht in:	Environmental health perspectives 1998-12, Vol.106 Suppl 6 (suppl 6), p.1385-1393
Hauptverfasser:	Yang, R S, Thomas, R S, Gustafson, D L, Campain, J, Benjamin, S A, Verhaar, H J, Mumtaz, M M
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Humans Models, Biological Pharmacokinetics Predictive Value of Tests Structure-Activity Relationship Toxicity Tests - methods
Online-Zugang:	Volltext
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