Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients

The functional single-nucleotide polymorphism (SNP) of the gene PTPN22 is a susceptibility locus for rheumatoid arthritis (RA). The study presented here describes the association of the PTPN22 1858T allele with RA in a German patient cohort; 390 patients with RA and 349 controls were enrolled in the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Arthritis research & therapy 2006-01, Vol.8 (3), p.R75-R75, Article R75
Hauptverfasser:	Pierer, Matthias, Kaltenhäuser, Sylke, Arnold, Sybille, Wahle, Matthias, Baerwald, Christoph, Häntzschel, Holm, Wagner, Ulf
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - enzymology Arthritis, Rheumatoid - genetics Female Gene Frequency Germany Humans Male Polymorphism, Single Nucleotide Protein Tyrosine Phosphatase, Non-Receptor Type 22 Protein Tyrosine Phosphatases - genetics Risk Assessment Sex Characteristics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!