HDAC6-p97/VCP controlled polyubiquitin chain turnover

HDAC6 is a unique cytoplasmic deacetylase capable of interacting with ubiquitin. Using a combination of biophysical, biochemical and biological approaches, we have characterized the ubiquitin‐binding domain of HDAC6, named ZnF‐UBP, and investigated its biological functions. These studies show that t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The EMBO journal 2006-07, Vol.25 (14), p.3357-3366
Hauptverfasser:	Boyault, Cyril, Gilquin, Benoit, Zhang, Yu, Rybin, Vladimir, Garman, Elspeth, Meyer-Klaucke, Wolfram, Matthias, Patrick, Müller, Christoph W, Khochbin, Saadi
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Accumulation Adenosine Triphosphatases Aggregates Amino Acid Sequence Animals Binding sites Biochemistry Biodegradation Cell Cycle Proteins - physiology CFTR Chlorocebus aethiops COS Cells EMBO24 EMBO31 HeLa Cells Histone Deacetylase 6 Histone Deacetylases - deficiency Histone Deacetylases - genetics Histone Deacetylases - physiology Humans Ions Mice Mice, Knockout Molecular biology Molecular Sequence Data neurodegenerative diseases Polyubiquitin - metabolism Protein Folding Proteins USP Valosin Containing Protein zinc-finger
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!