Enhanced Response to Ozone Exposure during the Follicular Phase of the Menstrual Cycle

Exposure to ozone ( O3), a toxic component of photochemical smog, results in significant airway inflammation, respiratory discomfort, and pulmonary function impairment. These effects can be reduced via pretreatment with anti-inflammatory agents. Progesterone, a gonadal steroid, is known to reduce ge...

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Veröffentlicht in:	Environmental health perspectives 1993-08, Vol.101 (3), p.242-244
Hauptverfasser:	Fox, Susan D., Adams, William C., Brookes, Katherine A., Lasley, Bill L.
Format:	Artikel
Sprache:	eng
Schlagworte:	551000 - Physiological Systems 560300 - Chemicals Metabolism & Toxicology Administration, Inhalation Adult ANTIPYRETICS BASIC BIOLOGICAL SCIENCES BIOLOGICAL EFFECTS BODY Brief Reports CENTRAL NERVOUS SYSTEM DEPRESSANTS DRUGS Endometrium ENVIRONMENTAL EXPOSURE Estrogens - urine Female FEMALES Follicular Phase - drug effects Follicular Phase - physiology Follicular Phase - urine HORMONES Humans INFLAMMATION KETONES Lung - drug effects Lung - physiology LUNGS Luteal Phase - drug effects Luteal Phase - physiology Luteal Phase - urine Male MENSTRUAL CYCLE ORGANIC COMPOUNDS ORGANS OZONE Ozone - adverse effects PATHOLOGICAL CHANGES PREGNANES PROGESTERONE Progesterone - urine Prostaglandins Prostaglandins - metabolism Pulmonary functions RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RESPIRATORY SYSTEM RESPONSE MODIFYING FACTORS SMOG STEROID HORMONES STEROIDS SYMPTOMS Vital capacity
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