Hepatic Nuclear Ploidy Distribution of Dietary-Restricted Mice

Hepatic parenchymal cells in most adult mammals are polyploid, with most of the cells in the quiescent or low-proliferation state. Polyploidization has been related to carcinogenesis and aging, and both end points are significantly affected by dietary restriction (DR). Direct measures of hepatic nuc...

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Veröffentlicht in:Environmental health perspectives 1993-12, Vol.101 (Suppl 5), p.229-233
Hauptverfasser: Lu, Ming H., Hinson, William G., He, Dansha, Turturro, Angelo, Hart, Ronald W.
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Sprache:eng
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