Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors

Type 1 interferon–producing cells (IPCs), also known as plasmacytoid dendritic cell (DC) precursors, represent the key effectors in antiviral innate immunity and triggers for adaptive immune responses. IPCs play important roles in the pathogenesis of systemic lupus erythematosus (SLE) and in modulat...

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Veröffentlicht in:	Blood 2004-04, Vol.103 (7), p.2547-2553
Hauptverfasser:	Chen, Wei, Antonenko, Svetlana, Sederstrom, Joel M., Liang, Xueqing, Chan, Anissa S.H., Kanzler, Holger, Blom, Bianca, Blazar, Bruce R., Liu, Yong-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - analysis Antigens, CD34 - analysis Biological and medical sciences Cell Culture Techniques - methods Cell Differentiation - immunology Cell differentiation, maturation, development, hematopoiesis Cell Division - physiology Cell physiology Cells, Cultured Dendritic Cells - cytology Dendritic Cells - immunology Fetus Fundamental and applied biological sciences. Psychology Gestational Age Granulocyte Colony-Stimulating Factor - pharmacology Hematopoiesis - physiology Hematopoietic Stem Cell Mobilization - methods Hematopoietic Stem Cells - cytology Humans Lymphocyte Activation Membrane Proteins - physiology Molecular and cellular biology Plasma Cells - cytology Plasma Cells - immunology T-Lymphocytes - immunology Thrombopoietin - physiology
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