Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors

Autologous dendritic cells (DCs) transfected with mRNA encoding prostate-specific antigen (PSA) are able to stimulate potent, T cell–mediated antitumor immune responses in vitro. A phase I trial was performed to evaluate this strategy for safety, feasibility, and efficacy to induce T cell responses...

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Veröffentlicht in:	The Journal of clinical investigation 2002-02, Vol.109 (3), p.409-417
Hauptverfasser:	Heiser, Axel, Coleman, Doris, Dannull, Jens, Yancey, Donna, Maurice, Margaret A., Lallas, Costas D., Dahm, Philipp, Niedzwiecki, Donna, Gilboa, Eli, Vieweg, Johannes
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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