Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle

During the development of skeletal muscle, myoblasts withdraw from the cell cycle and differentiate into myotubes. The insulin-like growth factors IGF-I and IGF-II, through their cognate tyrosine kinase receptor (IGF-I receptor), are known to play a role in this process. After withdrawal of myoblast...

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Veröffentlicht in:	The Journal of clinical investigation 2002-02, Vol.109 (3), p.347-355
Hauptverfasser:	Fernández, Ana M., Dupont, Joëlle, Farrar, Roger P., Lee, Sukho, Stannard, Bethel, Le Roith, Derek
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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