DNA Damage Measured by the Comet Assay in Head and Neck Cancer Patients Treated with Tirapazamine1

Tirapazamine (TPZ) [3-amino-1,2,4-benzotriazine 1,4-dioxide, SR4233, WIN 59075, and Tirazone ™ ] is a novel anticancer drug that is selectively activated by the low oxygen environment in solid tumors. By killing the radioresistant hypoxic cells, TPZ potentiates the antitumor efficacy of fractionated...

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Veröffentlicht in:	Neoplasia (New York, N.Y.) N.Y.), 1999-11, Vol.1 (5), p.461-467
Hauptverfasser:	Dorie, Mary Jo, Kovacs, Mary S, Gabalski, Edward C, Adam, Markus, Le, Quynh-T, Bloch, Daniel A, Pinto, Harlan A, Terris, David J, Brown, J Martin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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