Influence of cimetidine on pharmacokinetics of propranolol

Whole-blood propranolol concentrations were estimated for 12 hours after a single 80 mg oral dose was given in six patients taking cimetidine and two weeks after they had stopped the drug. Mean blood propranolol concentrations were higher throughout the sampling period when the patients were taking...

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Veröffentlicht in:	BMJ 1981-06, Vol.282 (6280), p.1917-1919
Hauptverfasser:	Heagerty, A M, Donovan, M A, Castleden, C M, Pohl, J F, Patel, L, Hedges, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anticoagulants Bioavailability Biological Availability Blood Blood plasma Cimetidine - blood Cimetidine - pharmacology Clinical Research Dosage Female Guanidines - pharmacology Heparin Humans Kinetics Liver Male Middle Aged Pharmacokinetics Propranolol - blood
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