Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus

Virus-specific CD8 + T cells traffic to infected tissues to promote clearance of infection. We used herpes simplex virus type 2 (HSV-2) as a model system to investigate CD8 + T cell trafficking to the skin in humans. Using human leukocyte antigen (HLA) class I tetramers, we observed that HSV-specifi...

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Veröffentlicht in:The Journal of clinical investigation 2002-08, Vol.110 (4), p.537-548
Hauptverfasser: Koelle, David M., Liu, Zhi, McClurkan, Christopher M., Topp, Max S., Riddell, Stanley R., Pamer, Eric G., Johnson, Andrew S., Wald, Anna, Corey, Lawrence
Format: Artikel
Sprache:eng
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