Hypoparathyroidism and hypocalcaemia during treatment for acute leukaemia

Disturbed calcium metabolism can occur during treatment of acute leukaemia. The authors report findings of a reduction in calcium absorption after metronidazole 800 mg/day for 10 days concurrently with neomycin 1 g day for three days in 11 patients with contaminated small bowel syndrome. Neomycin ma...

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Veröffentlicht in:BMJ 1982-05, Vol.284 (6327), p.1472-1473
Hauptverfasser: Robinson, Anne, Maher, Kieran, O'Moore, Rory, Keogh, Brian, Weir, D. G., Coffey, L., McCann, S. R.
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container_end_page 1473
container_issue 6327
container_start_page 1472
container_title BMJ
container_volume 284
creator Robinson, Anne
Maher, Kieran
O'Moore, Rory
Keogh, Brian
Weir, D. G.
Coffey, L.
McCann, S. R.
description Disturbed calcium metabolism can occur during treatment of acute leukaemia. The authors report findings of a reduction in calcium absorption after metronidazole 800 mg/day for 10 days concurrently with neomycin 1 g day for three days in 11 patients with contaminated small bowel syndrome. Neomycin may cause calcium malabsorption, the precise mechanism being obscure and perhaps related to depressed mucosal cell function. Metronidazole, has not been reported to affect calcium balance.
doi_str_mv 10.1136/bmj.284.6327.1472-c
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source Jstor Complete Legacy; MEDLINE; PubMed Central
subjects Anthracyclines
Calcium
Correspondence
Humans
Hypocalcemia
Hypocalcemia - chemically induced
Kidney failure
Letter
Leukemia
Metronidazole - adverse effects
Neomycin - adverse effects
Short Bowel Syndrome - complications
title Hypoparathyroidism and hypocalcaemia during treatment for acute leukaemia
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