Adjuvant‐dependent modulation of Th1 and Th2 responses to immunization with β‐amyloid

The role of adjuvant on the Th1 and Th2 immune responses to Aβ‐immunotherapy (Aβ42 peptide) was examined in wild‐type mice. Fine epitope analysis with overlapping oligomers of the Aβ42 sequence identified the 1–15 region as a dominant B cell epitope. The 6–20 peptide was recognized only weakly by an...

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