THE ACTION OF ATROPINE ON PANCREATIC SECRETION

THE ACTION OF ATROPINE ON PANCREATIC SECRETION

The action of atropine, in preventing pancreatic secretion in response to a parasympathomimetic drug, is analysed. Atropine does not appear to affect the uptake of glycine by the pancreatic cell, or the incorporation of radioactive amino acids into the total pancreatic tissue proteins, or into the p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:British Journal of Pharmacology and Chemotherapy 1958-03, Vol.13 (1), p.71-73
Hauptverfasser: JUNQUEIRA, L. C U., ROTHSCHILD, HANNA A., VUGMAN, I.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acids
Amylases
Animals
Atropine - pharmacology
Old Medline
Pancreas - physiology
Pancreatic Juice
Proteins
Rats
Secretory Vesicles
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The action of atropine, in preventing pancreatic secretion in response to a parasympathomimetic drug, is analysed. Atropine does not appear to affect the uptake of glycine by the pancreatic cell, or the incorporation of radioactive amino acids into the total pancreatic tissue proteins, or into the proteins of the zymogen granules. The rate of amylase resynthesis in stimulated glands is not affected by atropine. It is suggested that atropine blocks pancreatic secretion in rats by blocking the extrusion of zymogen granules.
ISSN:0366-0826
1476-5381
DOI:10.1111/j.1476-5381.1958.tb00193.x