The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif

Modified nucleosides play an important role in structure and function of tRNA. We have determined the solution structure of the anticodon stem–loop (ASL) of initiator tRNA of Schizosaccharomyces pombe. The incorporation of N6-threonylcarbamoyladenosine at the position 3′ to the anticodon triplet (t6...

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Veröffentlicht in:	Nucleic acids research 2006, Vol.34 (10), p.2878-2886
Hauptverfasser:	Lescrinier, Eveline, Nauwelaerts, Koen, Zanier, Katia, Poesen, Koen, Sattler, Michael, Herdewijn, Piet
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - chemistry Anticodon - chemistry Biochemistry, Molecular Biology Life Sciences Models, Molecular Nuclear Magnetic Resonance, Biomolecular Nucleic Acid Conformation RNA, Fungal - chemistry RNA, Transfer, Lys - chemistry RNA, Transfer, Met - chemistry Schizosaccharomyces - genetics Solutions Threonine - analogs & derivatives Threonine - chemistry
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