Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes

The imprinted gene cluster at the telomeric end of mouse chromosome 7 contains a differentially methylated CpG island, KvDMR, that is required for the imprinting of multiple genes, including the genes encoding the maternally expressed placental-specific transcription factor ASCL2, the cyclin-depende...

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Veröffentlicht in:	Genes & development 2006-05, Vol.20 (10), p.1268-1282
Hauptverfasser:	Mancini-Dinardo, Debora, Steele, Scott J S, Levorse, John M, Ingram, Robert S, Tilghman, Shirley M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CpG Islands Cyclin-Dependent Kinase Inhibitor p57 - genetics DNA Methylation Genomic Imprinting - genetics Methyltransferases - genetics Mice Promoter Regions, Genetic - genetics Research Paper RNA, Antisense - genetics RNA, Messenger, Stored - genetics RNA, Messenger, Stored - metabolism RNA, Untranslated - genetics Sequence Deletion Terminator Regions, Genetic Transcription, Genetic
Online-Zugang:	Volltext
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