Coexisting Domains in the Plasma Membranes of Live Cells Characterized by Spin-Label ESR Spectroscopy

The importance of membrane-based compartmentalization in eukaryotic cell function has become broadly appreciated, and a number of studies indicate that these eukaryotic cell membranes contain coexisting liquid-ordered ( L o) and liquid-disordered ( L d) lipid domains. However, the current evidence f...

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Veröffentlicht in:	Biophysical journal 2006-06, Vol.90 (12), p.4452-4465
Hauptverfasser:	Swamy, Musti J., Ciani, Laura, Ge, Mingtao, Smith, Andrew K., Holowka, David, Baird, Barbara, Freed, Jack H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - chemistry Cells Cercopithecus aethiops CHO Cells Computer Simulation COS Cells Cricetinae Cricetulus Electron Spin Resonance Spectroscopy - methods Lipids Membrane Lipids - chemistry Membrane Microdomains - chemistry Membranes Mice Models, Biological Models, Molecular Molecular Conformation NIH 3T3 Cells Phase Transition Plasma Spin Labels Temperature
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