The Role of Human Glutathione Transferases and Epoxide Hydrolases in the Metabolism of Xenobiotics

Human glutathione transferases (GSTs) are a multigene family of enzymes that are involved in the metabolism of a wide range of electrophilic compounds of both exogenous and endogenous origin. GSTs are generally recognized as detoxifying enzymes by catalyzing the conjugation of these compounds with g...

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Veröffentlicht in:	Environmental health perspectives 1997-06, Vol.105 (Suppl 4), p.791-799
Hauptverfasser:	Seidegard, J, Ekstrom, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Enzymes Epoxide Hydrolases - genetics Epoxide Hydrolases - physiology Epoxy compounds Genes Genetic variation Glutathione Transferase - classification Glutathione Transferase - genetics Glutathione Transferase - physiology Goods and services tax Humans Individual Susceptibility to Toxicants Leukotrienes Liver Oxides Polymorphism, Genetic Substrate specificity Xenobiotics Xenobiotics - metabolism
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