Antigen Structural Requirements for Recognition by a Cyclobutane Thymine Dimer-Specific Monoclonal Antibody

A monoclonal antibody (TDM-2) specific to a UV-induced cyclobutane pyrimidine dimer (T[c/s-syn]T) has previously been established; however, the immunization had used UV-irradiated calf-thymus DNA containing a heterogeneous mixture of photoproduct sites. We investigated here the structural requiremen...

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Veröffentlicht in:	Nucleic acids research 1997-10, Vol.25 (19), p.3889-3894
Hauptverfasser:	Komatsu, Yasuo, Tsujino, Tomomi, Suzuki, Tomonori, Nikaido, Osamu, Ohtsuka, Eiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antibody Specificity Antigens - chemistry Base Sequence Binding Sites Binding, Competitive Cattle DNA - chemistry DNA - immunology Enzyme-Linked Immunosorbent Assay In Vitro Techniques Mice Molecular Structure Oligodeoxyribonucleotides - chemical synthesis Oligodeoxyribonucleotides - chemistry Oligodeoxyribonucleotides - immunology Pyrimidine Dimers - chemical synthesis Pyrimidine Dimers - chemistry Pyrimidine Dimers - immunology
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