Population Toxicokinetics of Benzene

In assessing the distribution and metabolism of toxic compounds in the body, measurements are not always feasible for ethical or technical reasons. Computer modeling offers a reasonable alternative, but the variability and complexity of biological systems pose unique challenges in model building and...

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Veröffentlicht in:	Environmental health perspectives 1996-12, Vol.104 (suppl 6), p.1405-1411
Hauptverfasser:	Bois, Frédéric Yves, Jackson, Elise T., Pekari, Kaija, Smith, Martyn T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayes Theorem Benzene - metabolism Benzene - pharmacokinetics Benzene - toxicity Bone marrow Bone Marrow - metabolism Bone metabolism Chemical hazards Computer Simulation Drug design Humans Liver Liver - metabolism Male Markov Chains Mathematical independent variables Metabolism Models, Biological Pharmacokinetics Pharmacokinetics and Modeling Phenols Population distributions Tissue Distribution
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