Influence of the Nature of the Porphyrin Ligand on the Nuclease Activity of Metalloporphyrin-Oligonucleotide Conjugates Designed with Cationic, Hydrophobic or Anionic Metalloporphyrins

The synthesis of metalloporphyrin-oligonucleotide conjugates with different metalloporphyrin moieties are described as well as the comparison of their in vitro nuclease efficiency toward a single-stranded DNA target. Between cationic, anionic and hydrophobic manganese porphyrins covalently linked to...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 1997-03, Vol.25 (5), p.1022-1027
Hauptverfasser:	Mestre, Béatrice, Pitié, Marguerite, Loup, Christophe, Claparols, Catherine, Pratviel, Geneviève, Meunier, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	Anions Cations Deoxyribonucleases - chemistry Deoxyribonucleases - metabolism DNA, Single-Stranded - chemical synthesis DNA, Single-Stranded - metabolism Ligands Metalloporphyrins - chemistry Metalloporphyrins - metabolism Oligonucleotides - chemistry Oligonucleotides - metabolism Porphyrins - chemistry Porphyrins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!