Enzymatic Activities Involved in the DNA Resynthesis Step of Nucleotide Excision Repair Are Firmly Attached to Chromatin

In this study the role of nuclear architecture in nucleotide excision repair (NER) was investigated by gentle dismantling of the cell and probing the capability of chromatin to carry out repair in vitro. The rationale behind this approach is that compartmentalization of NER at nuclear structures wou...

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Veröffentlicht in:	Nucleic acids research 1997-03, Vol.25 (5), p.1056-1063
Hauptverfasser:	Bouayadi, Khalil, van der Leer-van Hoffen, Anneke, Balajee, A. S., Natarajan, A. T., van Zeeland, Albert A., Mullenders, Leon H. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cells, Cultured Chromatin - metabolism DNA - biosynthesis DNA Repair DNA Replication Enzymes - metabolism Fibroblasts - cytology Fibroblasts - metabolism Fibroblasts - radiation effects Humans Nucleotides Radiation Tolerance Transcription, Genetic Ultraviolet Rays
Online-Zugang:	Volltext
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