Stereoselective disposition of ibuprofen enantiomers in man

This study has examined the stereoselective disposition of the enantiomers of ibuprofen in four healthy male subjects following separate administration of racemic ibuprofen (800 mg) and of each enantiomer (400 mg). A mean of 63 +/‐ 6% of an administered dose of R(‐) ibuprofen was stereospecifically...

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Veröffentlicht in:	British journal of clinical pharmacology 1985-05, Vol.19 (5), p.669-674
Hauptverfasser:	Lee, EJ, Williams, K, Day, R, Graham, G, Champion, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Glucuronates - metabolism Half-Life Humans Ibuprofen - blood Ibuprofen - metabolism Kinetics Male Medical sciences Middle Aged Pharmacology. Drug treatments Stereoisomerism
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