Increased platelet membrane [3H]‐LSD binding in patients on chronic neuroleptic treatment

Using a [3H]‐lysergic acid diethylamide [(3H]‐LSD) binding technique, platelet 5‐hydroxytryptamine (5‐HT) receptor number and affinity were compared in schizophrenics treated with depot thioxanthenes and phenothiazines and controls. There was an approximately 30% increase in platelet receptor number...

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Veröffentlicht in:	British journal of clinical pharmacology 1985-04, Vol.19 (4), p.453-457
Hauptverfasser:	Schachter, M, Geaney, DP, Grahame‐Smith, DG, Cowen, PJ, Elliott, JM
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aging Antipsychotic Agents - pharmacology Biological and medical sciences Blood Platelets - metabolism Cell Membrane - metabolism Female Humans Kinetics Lysergic Acid Diethylamide - blood Lysergic Acid Diethylamide - metabolism Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Receptors, Serotonin - metabolism Schizophrenia - blood Sex Factors Time Factors
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