The N-Terminal DNA-Binding Domain of Rad52 Promotes RAD51-Independent Recombination in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the Rad52 protein plays a role in both RAD51-dependent and RAD51-independent recombination pathways. We characterized a rad52 mutant, rad52-329, which lacks the C-terminal Rad51-interacting domain, and studied its role in RAD51-independent recombination. The rad52-329 mu...

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Veröffentlicht in:	Genetics (Austin) 2003-12, Vol.165 (4), p.1703-1715
Hauptverfasser:	Tsukamoto, Mariko, Yamashita, Kentaro, Miyazaki, Toshiko, Shinohara, Miki, Shinohara, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Cell Division Cell Survival Deoxyribonucleic acid DNA DNA, Fungal - genetics DNA, Fungal - metabolism DNA-Binding Proteins - physiology Genetic recombination Genetics Mutagenesis Mutation Rad51 Recombinase Rad52 DNA Repair and Recombination Protein rad52 gene Rad52 protein Recombination, Genetic Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins Telomerase - physiology Telomere - genetics Yeast
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