Transposon Mutagenesis of the Mouse Germline

Sleeping Beauty is a synthetic "cut-and-paste" transposon of the Tc1/mariner class. The Sleeping Beauty transposase (SB) was constructed on the basis of a consensus sequence obtained from an alignment of 12 remnant elements cloned from the genomes of eight different fish species. Transposi...

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Bibliographische Detailangaben

Veröffentlicht in:	Genetics (Austin) 2003-09, Vol.165 (1), p.243-256
Hauptverfasser:	Carlson, Corey M, Dupuy, Adam J, Fritz, Sabine, Roberg-Perez, Kevin J, Fletcher, Colin F, Largaespada, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosome Mapping Comparative analysis DNA Transposable Elements Genetic Vectors Genetics Genomics Germ Cells Mice Mice, Transgenic Mutagenesis, Insertional - methods Mutation Rodents Transposases Transposon mutagenesis
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