HIV Tat-mediated transcriptional regulation of proteasome protein cleavage specificity

The major antigen-adapted immune response protecting a vertebrate against virus infection is that mediated by CTLs (cytotoxic T-lymphocytes). CTLs destroy virus-infected cells, thereby containing the infection. They are activated by recognition of peptide antigens or epitopes, presented to them in t...

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Veröffentlicht in:	Biochemical journal 2006-06, Vol.396 (2), p.e13-e15
Hauptverfasser:	Aresté, Cristina, Blackbourn, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cysteine Endopeptidases - metabolism Gene Expression Regulation, Viral Gene Products, tat - pharmacology Human immunodeficiency virus Humans Interferon Regulatory Factor-1 - metabolism Models, Biological Proteasome Endopeptidase Complex - genetics Proteasome Endopeptidase Complex - metabolism STAT1 Transcription Factor - metabolism Transcription, Genetic
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