A Linkage Map of an F2 Hybrid Population of Antirrhinum majus and A. molle
To increase the utility of Antirrhinum for genetic and evolutionary studies, we constructed a molecular linkage map for an interspecific hybrid A. majus x A. molle. An F(2) population (n = 92) was genotyped at a minimum of 243 individual loci. Although distorted transmission ratios were observed at...
Gespeichert in:
| Veröffentlicht in: | Genetics (Austin) 2003-02, Vol.163 (2), p.699-710 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 710 |
|---|---|
| container_issue | 2 |
| container_start_page | 699 |
| container_title | Genetics (Austin) |
| container_volume | 163 |
| creator | Schwarz-Sommer, Zsuzsanna de Andrade Silva, Eugenia Berndtgen, Rita Lonnig, Wolf-Ekkehard Muller, Andreas Nindl, Ingo Stuber, Kurt Wunder, Jorg Saedler, Heinz Gubitz, Thomas Borking, Amanda Golz, John F Ritter, Enrique Hudson, Andrew |
| description | To increase the utility of Antirrhinum for genetic and evolutionary studies, we constructed a molecular linkage map for an interspecific hybrid A. majus x A. molle. An F(2) population (n = 92) was genotyped at a minimum of 243 individual loci. Although distorted transmission ratios were observed at marker loci throughout the genome, a mapping strategy based on a fixed framework of codominant markers allowed the loci to be placed into eight robust linkage groups consistent with the haploid chromosome number of Antirrhinum. The mapped loci included 164 protein-coding genes and a similar number of unknown sequences mapped as AFLP, RFLP, ISTR, and ISSR markers. Inclusion of sequences from mutant loci allowed provisional alignment of classical and molecular linkage groups. The total map length was 613 cM with an average interval of 2.5 cM, but most of the loci were aggregated into clusters reducing the effective distance between markers. Potential causes of transmission ratio distortion and its effects on map construction were investigated. This first molecular linkage map for Antirrhinum should facilitate further mapping of mutations, major QTL, and other coding sequences in this model genus. |
| doi_str_mv | 10.1093/genetics/163.2.699 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1462440</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>675769771</sourcerecordid><originalsourceid>FETCH-LOGICAL-c327t-b4fbfc916b005201e29e3140a2e9a248d8cbce00953fcbb43d5df1457232ea193</originalsourceid><addsrcrecordid>eNpdkcFuEzEQhi0EoqHwAhyQxaG3TT2217u-IEUVpaBU5QBny-v1Jg5eO9i7RH37umogwGkO8_2_ZvQh9BbIEohklxsb7ORMvgTBlnQppHyGFiA5q6hg8BwtCAFRiYbBGXqV844QImTdvkRnQAW0nDQL9GWF1y780BuLb_UexwHrgK8pvrnvkuvx17ifvZ5cDI-rVZhcSlsX5hGPejfnAvd4tcRj9N6-Ri8G7bN9c5zn6Pv1x29XN9X67tPnq9W6Mow2U9XxoRuMBNERUlMClkrLgBNNrdSUt31rOmMJkTUbTNdx1tf9ALxuKKNWg2Tn6MNT737uRtsbG6akvdonN-p0r6J26t9NcFu1ib8UcEE5J6Xg4liQ4s_Z5kmNLhvrvQ42zlk1jDSCtqyA7_8Dd3FOoTynKHCgrBa8QPQJMinmnOzw5xIg6tGT-u1JFU-KquKphN79_cMpchRzunHrNtuDS1blUXtfcFCHw-HU9ABfE5zj</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>214123564</pqid></control><display><type>article</type><title>A Linkage Map of an F2 Hybrid Population of Antirrhinum majus and A. molle</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Alma/SFX Local Collection</source><creator>Schwarz-Sommer, Zsuzsanna ; de Andrade Silva, Eugenia ; Berndtgen, Rita ; Lonnig, Wolf-Ekkehard ; Muller, Andreas ; Nindl, Ingo ; Stuber, Kurt ; Wunder, Jorg ; Saedler, Heinz ; Gubitz, Thomas ; Borking, Amanda ; Golz, John F ; Ritter, Enrique ; Hudson, Andrew</creator><creatorcontrib>Schwarz-Sommer, Zsuzsanna ; de Andrade Silva, Eugenia ; Berndtgen, Rita ; Lonnig, Wolf-Ekkehard ; Muller, Andreas ; Nindl, Ingo ; Stuber, Kurt ; Wunder, Jorg ; Saedler, Heinz ; Gubitz, Thomas ; Borking, Amanda ; Golz, John F ; Ritter, Enrique ; Hudson, Andrew</creatorcontrib><description>To increase the utility of Antirrhinum for genetic and evolutionary studies, we constructed a molecular linkage map for an interspecific hybrid A. majus x A. molle. An F(2) population (n = 92) was genotyped at a minimum of 243 individual loci. Although distorted transmission ratios were observed at marker loci throughout the genome, a mapping strategy based on a fixed framework of codominant markers allowed the loci to be placed into eight robust linkage groups consistent with the haploid chromosome number of Antirrhinum. The mapped loci included 164 protein-coding genes and a similar number of unknown sequences mapped as AFLP, RFLP, ISTR, and ISSR markers. Inclusion of sequences from mutant loci allowed provisional alignment of classical and molecular linkage groups. The total map length was 613 cM with an average interval of 2.5 cM, but most of the loci were aggregated into clusters reducing the effective distance between markers. Potential causes of transmission ratio distortion and its effects on map construction were investigated. This first molecular linkage map for Antirrhinum should facilitate further mapping of mutations, major QTL, and other coding sequences in this model genus.</description><identifier>ISSN: 0016-6731</identifier><identifier>ISSN: 1943-2631</identifier><identifier>EISSN: 1943-2631</identifier><identifier>DOI: 10.1093/genetics/163.2.699</identifier><identifier>PMID: 12618407</identifier><identifier>CODEN: GENTAE</identifier><language>eng</language><publisher>United States: Genetics Soc America</publisher><subject>Antirrhinum - genetics ; Chromosome Mapping ; Evolution ; Genetic Linkage ; Genetics ; Hybridization ; Hybridization, Genetic ; Polymorphism, Genetic ; Sequence Analysis, DNA</subject><ispartof>Genetics (Austin), 2003-02, Vol.163 (2), p.699-710</ispartof><rights>Copyright Genetics Society of America Feb 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c327t-b4fbfc916b005201e29e3140a2e9a248d8cbce00953fcbb43d5df1457232ea193</citedby><cites>FETCH-LOGICAL-c327t-b4fbfc916b005201e29e3140a2e9a248d8cbce00953fcbb43d5df1457232ea193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,886,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12618407$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schwarz-Sommer, Zsuzsanna</creatorcontrib><creatorcontrib>de Andrade Silva, Eugenia</creatorcontrib><creatorcontrib>Berndtgen, Rita</creatorcontrib><creatorcontrib>Lonnig, Wolf-Ekkehard</creatorcontrib><creatorcontrib>Muller, Andreas</creatorcontrib><creatorcontrib>Nindl, Ingo</creatorcontrib><creatorcontrib>Stuber, Kurt</creatorcontrib><creatorcontrib>Wunder, Jorg</creatorcontrib><creatorcontrib>Saedler, Heinz</creatorcontrib><creatorcontrib>Gubitz, Thomas</creatorcontrib><creatorcontrib>Borking, Amanda</creatorcontrib><creatorcontrib>Golz, John F</creatorcontrib><creatorcontrib>Ritter, Enrique</creatorcontrib><creatorcontrib>Hudson, Andrew</creatorcontrib><title>A Linkage Map of an F2 Hybrid Population of Antirrhinum majus and A. molle</title><title>Genetics (Austin)</title><addtitle>Genetics</addtitle><description>To increase the utility of Antirrhinum for genetic and evolutionary studies, we constructed a molecular linkage map for an interspecific hybrid A. majus x A. molle. An F(2) population (n = 92) was genotyped at a minimum of 243 individual loci. Although distorted transmission ratios were observed at marker loci throughout the genome, a mapping strategy based on a fixed framework of codominant markers allowed the loci to be placed into eight robust linkage groups consistent with the haploid chromosome number of Antirrhinum. The mapped loci included 164 protein-coding genes and a similar number of unknown sequences mapped as AFLP, RFLP, ISTR, and ISSR markers. Inclusion of sequences from mutant loci allowed provisional alignment of classical and molecular linkage groups. The total map length was 613 cM with an average interval of 2.5 cM, but most of the loci were aggregated into clusters reducing the effective distance between markers. Potential causes of transmission ratio distortion and its effects on map construction were investigated. This first molecular linkage map for Antirrhinum should facilitate further mapping of mutations, major QTL, and other coding sequences in this model genus.</description><subject>Antirrhinum - genetics</subject><subject>Chromosome Mapping</subject><subject>Evolution</subject><subject>Genetic Linkage</subject><subject>Genetics</subject><subject>Hybridization</subject><subject>Hybridization, Genetic</subject><subject>Polymorphism, Genetic</subject><subject>Sequence Analysis, DNA</subject><issn>0016-6731</issn><issn>1943-2631</issn><issn>1943-2631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkcFuEzEQhi0EoqHwAhyQxaG3TT2217u-IEUVpaBU5QBny-v1Jg5eO9i7RH37umogwGkO8_2_ZvQh9BbIEohklxsb7ORMvgTBlnQppHyGFiA5q6hg8BwtCAFRiYbBGXqV844QImTdvkRnQAW0nDQL9GWF1y780BuLb_UexwHrgK8pvrnvkuvx17ifvZ5cDI-rVZhcSlsX5hGPejfnAvd4tcRj9N6-Ri8G7bN9c5zn6Pv1x29XN9X67tPnq9W6Mow2U9XxoRuMBNERUlMClkrLgBNNrdSUt31rOmMJkTUbTNdx1tf9ALxuKKNWg2Tn6MNT737uRtsbG6akvdonN-p0r6J26t9NcFu1ib8UcEE5J6Xg4liQ4s_Z5kmNLhvrvQ42zlk1jDSCtqyA7_8Dd3FOoTynKHCgrBa8QPQJMinmnOzw5xIg6tGT-u1JFU-KquKphN79_cMpchRzunHrNtuDS1blUXtfcFCHw-HU9ABfE5zj</recordid><startdate>20030201</startdate><enddate>20030201</enddate><creator>Schwarz-Sommer, Zsuzsanna</creator><creator>de Andrade Silva, Eugenia</creator><creator>Berndtgen, Rita</creator><creator>Lonnig, Wolf-Ekkehard</creator><creator>Muller, Andreas</creator><creator>Nindl, Ingo</creator><creator>Stuber, Kurt</creator><creator>Wunder, Jorg</creator><creator>Saedler, Heinz</creator><creator>Gubitz, Thomas</creator><creator>Borking, Amanda</creator><creator>Golz, John F</creator><creator>Ritter, Enrique</creator><creator>Hudson, Andrew</creator><general>Genetics Soc America</general><general>Genetics Society of America</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>4T-</scope><scope>4U-</scope><scope>7QP</scope><scope>7SS</scope><scope>7TK</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20030201</creationdate><title>A Linkage Map of an F2 Hybrid Population of Antirrhinum majus and A. molle</title><author>Schwarz-Sommer, Zsuzsanna ; de Andrade Silva, Eugenia ; Berndtgen, Rita ; Lonnig, Wolf-Ekkehard ; Muller, Andreas ; Nindl, Ingo ; Stuber, Kurt ; Wunder, Jorg ; Saedler, Heinz ; Gubitz, Thomas ; Borking, Amanda ; Golz, John F ; Ritter, Enrique ; Hudson, Andrew</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c327t-b4fbfc916b005201e29e3140a2e9a248d8cbce00953fcbb43d5df1457232ea193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Antirrhinum - genetics</topic><topic>Chromosome Mapping</topic><topic>Evolution</topic><topic>Genetic Linkage</topic><topic>Genetics</topic><topic>Hybridization</topic><topic>Hybridization, Genetic</topic><topic>Polymorphism, Genetic</topic><topic>Sequence Analysis, DNA</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schwarz-Sommer, Zsuzsanna</creatorcontrib><creatorcontrib>de Andrade Silva, Eugenia</creatorcontrib><creatorcontrib>Berndtgen, Rita</creatorcontrib><creatorcontrib>Lonnig, Wolf-Ekkehard</creatorcontrib><creatorcontrib>Muller, Andreas</creatorcontrib><creatorcontrib>Nindl, Ingo</creatorcontrib><creatorcontrib>Stuber, Kurt</creatorcontrib><creatorcontrib>Wunder, Jorg</creatorcontrib><creatorcontrib>Saedler, Heinz</creatorcontrib><creatorcontrib>Gubitz, Thomas</creatorcontrib><creatorcontrib>Borking, Amanda</creatorcontrib><creatorcontrib>Golz, John F</creatorcontrib><creatorcontrib>Ritter, Enrique</creatorcontrib><creatorcontrib>Hudson, Andrew</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Genetics (Austin)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schwarz-Sommer, Zsuzsanna</au><au>de Andrade Silva, Eugenia</au><au>Berndtgen, Rita</au><au>Lonnig, Wolf-Ekkehard</au><au>Muller, Andreas</au><au>Nindl, Ingo</au><au>Stuber, Kurt</au><au>Wunder, Jorg</au><au>Saedler, Heinz</au><au>Gubitz, Thomas</au><au>Borking, Amanda</au><au>Golz, John F</au><au>Ritter, Enrique</au><au>Hudson, Andrew</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Linkage Map of an F2 Hybrid Population of Antirrhinum majus and A. molle</atitle><jtitle>Genetics (Austin)</jtitle><addtitle>Genetics</addtitle><date>2003-02-01</date><risdate>2003</risdate><volume>163</volume><issue>2</issue><spage>699</spage><epage>710</epage><pages>699-710</pages><issn>0016-6731</issn><issn>1943-2631</issn><eissn>1943-2631</eissn><coden>GENTAE</coden><abstract>To increase the utility of Antirrhinum for genetic and evolutionary studies, we constructed a molecular linkage map for an interspecific hybrid A. majus x A. molle. An F(2) population (n = 92) was genotyped at a minimum of 243 individual loci. Although distorted transmission ratios were observed at marker loci throughout the genome, a mapping strategy based on a fixed framework of codominant markers allowed the loci to be placed into eight robust linkage groups consistent with the haploid chromosome number of Antirrhinum. The mapped loci included 164 protein-coding genes and a similar number of unknown sequences mapped as AFLP, RFLP, ISTR, and ISSR markers. Inclusion of sequences from mutant loci allowed provisional alignment of classical and molecular linkage groups. The total map length was 613 cM with an average interval of 2.5 cM, but most of the loci were aggregated into clusters reducing the effective distance between markers. Potential causes of transmission ratio distortion and its effects on map construction were investigated. This first molecular linkage map for Antirrhinum should facilitate further mapping of mutations, major QTL, and other coding sequences in this model genus.</abstract><cop>United States</cop><pub>Genetics Soc America</pub><pmid>12618407</pmid><doi>10.1093/genetics/163.2.699</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0016-6731 |
| ispartof | Genetics (Austin), 2003-02, Vol.163 (2), p.699-710 |
| issn | 0016-6731 1943-2631 1943-2631 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1462440 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Antirrhinum - genetics Chromosome Mapping Evolution Genetic Linkage Genetics Hybridization Hybridization, Genetic Polymorphism, Genetic Sequence Analysis, DNA |
| title | A Linkage Map of an F2 Hybrid Population of Antirrhinum majus and A. molle |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T21%3A32%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Linkage%20Map%20of%20an%20F2%20Hybrid%20Population%20of%20Antirrhinum%20majus%20and%20A.%20molle&rft.jtitle=Genetics%20(Austin)&rft.au=Schwarz-Sommer,%20Zsuzsanna&rft.date=2003-02-01&rft.volume=163&rft.issue=2&rft.spage=699&rft.epage=710&rft.pages=699-710&rft.issn=0016-6731&rft.eissn=1943-2631&rft.coden=GENTAE&rft_id=info:doi/10.1093/genetics/163.2.699&rft_dat=%3Cproquest_pubme%3E675769771%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=214123564&rft_id=info:pmid/12618407&rfr_iscdi=true |