A screen for genes involved in the anaphase proteolytic pathway identifies tsm1+, a novel Schizosaccharomyces pombe gene important for microtubule integrity

The growth of several mitotic mutants of Schizosaccharomyces pombe, including nuc2-663, is inhibited by the protease inhibitor N-Tosyl-L-Phenylalanine Chloromethyl Ketone (TPCK). Because nuc2(+) encodes a presumptive component of the Anaphase Promoting Complex, which is required for the ubiquitin-de...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genetics (Austin) 1998-07, Vol.149 (3), p.1251-1264
Hauptverfasser:	Grishchuk, E.L. (University of Colorado, Boulder, CO.), Howe, J.L, McIntosh, J.R
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaphase - genetics CARTE GENETIQUE Cell Cycle - genetics CELL DIVISION CETONAS CETONE CHROMOSOME SEGREGATION CYTOPLASMIC ORGANELLES DIVISION CELLULAIRE DIVISION CELULAR DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics FENOTIPOS Fungal Proteins - genetics GENE GENE LOCATION GENES GENETIC MAPPING GENETIC MAPS Genetic Testing Genetics Genotype INHIBIDORES DE PROTEINASAS INHIBITEUR DE PROTEINASES KETONES LOCALISATION DE GENE LOCALIZACION DE GENES MAPAS GENETICOS METAPHASE SPINDLE MICROTUBULE MICROTUBULES Microtubules - genetics Microtubules - ultrastructure MICROTUBULOS MITOSE MITOSIS Mitosis - genetics MITOTIC SPINDLE Models, Genetic Molecular biology Mutagenesis MUTANT MUTANTES MUTANTS Mutation N-TOSYL-L-PHENYLALANINE CHLOROMETHYL KETONE ORGANITE CELLULAIRE ORGANULOS CITOPLASMICOS PHENOTYPE PHENOTYPES PROTEINAS PROTEINASE INHIBITORS PROTEINE PROTEINS Saccharomyces cerevisiae Proteins Schizosaccharomyces - genetics Schizosaccharomyces - ultrastructure SCHIZOSACCHAROMYCES POMBE SUSCEPTIBILITY TATA-Binding Protein Associated Factors Tosylphenylalanyl Chloromethyl Ketone Transcription Factor TFIID Transcription Factors - biosynthesis Transcription Factors - genetics TSM1+ GENE
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!