Is the in-Frame Termination Signal of the Escherichia Coli Release Factor-2 Frameshift Site Weakened by a Particularly Poor Context?

The synthesis of release factor-2 (RF-2) in bacteria is regulated by a high efficiency +1 frameshifting event at an in-frame UGA stop codon. The stop codon does not specify the termination of synthesis efficiently because of several upstream stimulators for frameshifting. This study focusses on whet...

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Veröffentlicht in:	Nucleic acids research 1996-07, Vol.24 (14), p.2673-2678
Hauptverfasser:	Major, Louise L., Poole, Elizabeth S., Dalphin, Mark E., Mannering, Sally A., Tate, Warren P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Binding Sites Codon, Terminator DNA, Bacterial Escherichia coli Frameshifting, Ribosomal Molecular Sequence Data Peptide Termination Factors - biosynthesis Peptide Termination Factors - genetics RNA, Bacterial - genetics Terminator Regions, Genetic - genetics
Online-Zugang:	Volltext
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