Translational Repression Is Sufficient for Gene Silencing by Bacterial Small Noncoding RNAs in the Absence of mRNA Destruction

Stress-induced Hfq-binding small RNAs of Escherichia coli, SgrS and RyhB, down-regulate the expression of target mRNAs through base-pairing. These small RNAs form ribonucleoprotein complexes with Hfq and RNase E. The regulatory outcomes of the RNase E/Hfq/small RNA-containing ribonucleoprotein compl...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2006-03, Vol.103 (13), p.4858-4863
Hauptverfasser: Morita, Teppei, Mochizuki, Yukari, Aiba, Hiroji
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Sprache:eng
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