Hox Homeodomain Proteins Exhibit Selective Complex Stabilities with Pbx and DNA

Eight of the nine homeobox genes of the Hoxb locus encode proteins which contain a conserved hexapeptide motif upstream from the homeodomain. All eight proteins (Hoxb-1–Hoxb-8) bind to a target oligonucleotide in the presence of Pbx1a under conditions where minimal or no binding is detected for the...

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Veröffentlicht in:	Nucleic acids research 1996-03, Vol.24 (5), p.898-906
Hauptverfasser:	Shen, Wei-Fang, Chang, Ching-Pin, Rozenfeld, Sofia, Sauvageau, Guy, Humphries, R. Keith, Lu, Ming, Lawrence, H. Jeffrey, Cleary, Michael L., Largman, Corey
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence DNA - metabolism DNA-Binding Proteins - metabolism Homeodomain Proteins - metabolism Macromolecular Substances Molecular Sequence Data Pre-B-Cell Leukemia Transcription Factor 1 Protein Binding Proto-Oncogene Proteins - metabolism Sequence Analysis
Online-Zugang:	Volltext
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