A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors

Krüppel-type zinc finger (ZNF) motifs are prevalent components of transcription factor proteins in all eukaryotes. KRAB-ZNF proteins, in which a potent repressor domain is attached to a tandem array of DNA-binding zinc-finger motifs, are specific to tetrapod vertebrates and represent the largest cla...

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Veröffentlicht in:	Genome Research 2006-05, Vol.16 (5), p.669-677
Hauptverfasser:	Huntley, Stuart, Baggott, Daniel M, Hamilton, Aaron T, Tran-Gyamfi, Mary, Yang, Shan, Kim, Joomyeong, Gordon, Laurie, Branscomb, Elbert, Stubbs, Lisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Computational Biology Database Management Systems Databases, Genetic Evolution, Molecular Gene Expression Gene Expression Profiling Genome, Human Humans Internet Kruppel-Like Transcription Factors - genetics Multigene Family Phylogeny Primates Protein Structure, Tertiary Repressor Proteins - chemistry Repressor Proteins - genetics Resource Zinc Fingers - genetics
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