Opsonic human antibodies from an endemic population specific for a conserved epitope on the M protein of group A streptococci

This study demonstrates the presence of epitope‐specific opsonic human antibodies in a population living in an area endemic for group A streptococci (GAS) infection. Antibodies recognizing a conserved C‐terminal region epitope (p145, sequence in single letter amino acids: LRRDLDASREAKKQVEKALE) of th...

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Veröffentlicht in:	Immunology 1996-11, Vol.89 (3), p.331-337
Hauptverfasser:	BRANDT, E. R., HAYMAN, W. A., CURRIE, B., CARAPETIS, J., WOOD, Y., JACKSON, D. C., COOPER, J., MELROSE, W. D., SAUL, A. J., GOOD, M. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Factors Amino Acid Sequence Antibodies, Bacterial - blood Antibodies, Bacterial - isolation & purification Antigens, Bacterial Bacterial Outer Membrane Proteins Bacterial Proteins - immunology Binding, Competitive Carrier Proteins Child Child, Preschool Epitope Mapping Epitopes - immunology Humans Immunoglobulin G - immunology Infant Molecular Sequence Data Opsonin Proteins - blood Peptide Fragments - immunology Phagocytosis Streptococcus pyogenes Streptococcus pyogenes - immunology
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