A novel dehydroepiandrosterone analog improves functional recovery in a rat traumatic brain injury model

The purpose of this study was to investigate the efficacy of a novel steroid, fluasterone (DHEF, a dehydroepiandrosterone (DHEA) analog), at improving functional recovery in a rat model of traumatic brain injury (TBI). The lateral cortical impact model was utilized in two studies of efficacy and the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurotrauma 2003-05, Vol.20 (5), p.463-476
Hauptverfasser:	Malik, Amir S, Narayan, Raj K, Wendling, Woodrow W, Cole, Russell W, Pashko, Laura L, Schwartz, Arthur G, Strauss, Kenneth I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - drug effects Brain - metabolism Brain Injuries - drug therapy Cells, Cultured Cyclooxygenase 2 Dehydroepiandrosterone - administration & dosage Dehydroepiandrosterone - analogs & derivatives Dehydroepiandrosterone - pharmacology Dinoprostone - metabolism Glomerular Mesangium - drug effects Isoenzymes - drug effects Isoenzymes - metabolism Male Maze Learning - drug effects Middle Cerebral Artery - drug effects Muscle, Smooth, Vascular - drug effects Neuroprotective Agents - administration & dosage Neuroprotective Agents - pharmacology Organ Culture Techniques Prostaglandin-Endoperoxide Synthases - drug effects Prostaglandin-Endoperoxide Synthases - metabolism Rats Rats, Sprague-Dawley Recovery of Function - drug effects Reflex - drug effects Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!