eae36, a Locus on Mouse Chromosome 4, Controls Susceptibility to Experimental Allergic Encephalomyelitis in Older Mice and Mice Immunized in the Winter

Genetic factors are believed to contribute to multiple sclerosis (MS) susceptibility; however, strong evidence implicating intrinsic and environmental factors in the etiopathogenesis of MS also exists. Susceptibility to experimental allergic encephalomyelitis (EAE), the principal animal model of MS,...

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Veröffentlicht in:	Genetics (Austin) 2006-02, Vol.172 (2), p.1147-1153
Hauptverfasser:	Teuscher, Cory, Doerge, R. W, Fillmore, Parley D, Blankenhorn, Elizabeth P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Animals Crosses, Genetic Disease Encephalomyelitis, Autoimmune, Experimental - chemically induced Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Environmental conditions Genetic Markers Genetic Predisposition to Disease - genetics Immune system Immunization Infectious diseases Influence Investigations Laboratory animals Mice Mice, Inbred C57BL Mice, Inbred Strains Microsatellite Repeats Polymorphism, Single Nucleotide Seasons Tests
Online-Zugang:	Volltext
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